The first hint to crack the puzzle "Port on the Gulf of Mexico since the 16th century" is:

It is a word which contains 8 letters

The second hint to crack the puzzle "Port on the Gulf of Mexico since the 16th century" is:

It starts with letter v

The third hint to crack the puzzle "Port on the Gulf of Mexico since the 16th century" is:

It ends with letter z

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The answer for the puzzle "Port on the Gulf of Mexico since the 16th century" is: